TY - JOUR
T1 - Modeling the Influence of Treatment Accessibility and Treatment Compliance on the Dynamics of HIV/AIDS
AU - Ayoade , Abayomi Ayotunde
AU - Thota , Srinivasarao
AU - Shah , Zahir
JO - Journal of Nonlinear Modeling and Analysis
VL - 2
SP - 552
EP - 582
PY - 2025
DA - 2025/04
SN - 7
DO - http://doi.org/10.12150/jnma.2025.552
UR - https://global-sci.org/intro/article_detail/jnma/24015.html
KW - Isolation, incubation period, asymptomatic, symptomatic, equilibria.
AB - <p style="text-align: justify;">The invention of highly active antiretroviral treatment (HAART)
revolutionalized the treatment of HIV and brought hope to millions of individuals living with the virus. However, the eradication of HIV has proved
difficult owing to many factors including accessibility and treatment compliance, particularly among many individuals in low income countries. Thus, we
developed a model in terms of a system of nonlinear ordinary differential equations to assess the influence of inaccessibility of treatment and noncompliance
with treatment guidelines by the HIV infectives who are aware of their status
on the spread of HIV. The model was studied qualitatively and quantitatively
using the theory of reproductive ratio and the software Maple respectively.
The results of the analysis showed that early detection, treatment accessibility
and treatment compliance by the majority of the infectives who know their
status are crucial to the minimization of HIV incidence and prevalence.</p>